Expresión de búsqueda: TREFOIL FACTORS 
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Descriptor Inglés:   Trefoil Factors 
Descriptor Español:   Factores Trefoil 
Descriptor Portugués:   Fatores Trefoil 
Sinónimos Inglés:   TFF Peptides
Trefoil Factor Family Peptides
Trefoil Factor Family Proteins
Trefoil Peptides
Trefoil Proteins  
Categoría:   D12.644.937
Definición Inglés:   A family of small peptides expressed primarily by MUCOUS MEMBRANE EPITHELIAL CELLS in vertebrates. Their structure is highly conserved and is defined by a three-leaved (trefoil) domain of 42 or 43 amino acids; it includes six cysteines that create the trefoil structure through disulfide bridges. Trefoil peptides may form dimers with each other, or associate with MUCINS and other factors. They are important for maintaining epithelial integrity and for protection from noxious agents. 
Nota Histórica Inglés:   2017 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Número del Registro:   56552 
Identificador Único:   D000071162 

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